CFR 111 certification is a regulation created by the US Food and Drug Administration (FDA) to ensure that dietary supplement packaging is safe, accurately labeled, and meets quality control standards. The regulation includes requirements for packaging and labeling, as well as for testing and verifying the identity, purity, strength, and composition of dietary supplements. CFR 111 certification is particularly important for manufacturers and contract packagers of dietary supplements, as it helps to protect the integrity of the products and the health of consumers. Compliance with CFR 111 certification is mandatory for all companies that manufacture, package, label, or hold dietary supplements, and failure to comply can result in legal action by the FDA.